Abstract
Background: Quality of life is a significant indicator of the course treatment process, lifestyle, and the influence of other variables. The purpose of this study was to analyze the health-related quality of life (HRQoL) and its predictors among elderly persons. It allowed us to identify the most crucial factors influencing the HRQoL in the process of "good aging." Method: The systematic review followed the “Preferred Reporting Results of Systematic Reviews and Meta-Analyses” (PRISMA) guidelines. Three electronic databases (PubMed, MDPI, and Science Direct) were used to retrieve the data. Articles electronically accessible investigating the health-related quality of life in the elderly and the factors influencing it were included. Pertinent studies were assessed based on set inclusion and exclusion criteria, data were extracted to pore over the related variables and propositional values. The extract comprised information regarding general details, study details, participants, and results. Results: 15 articles were included in this systematic review including 11 cross-sectional, 2 prospective cohort studies, and 2 systematic reviews. These studies collected data from different countries with most being from China and South Korea between January 2013 and 2022. The most commonly used questionnaires were EQ-5D and SF-36. The studies showed poor HRQoL scores in females, institutionalized individuals, frail cancer patients, disabled ones, kidney non-transplanted patients on prolonged dialysis, and women suffering from depression. Good HRQoL scores were seen in older individuals with greater serum folate concentrations, good diet intake, receiving chemotherapy, high BMI, high level of physical activity, and those undergone kidney transplant and hip arthroplasty. Conclusion: Oldest-old had generically poor scores. Health policy formulators should place HRQoL among the elderly as a priority for providing socio-economic and psychological support, as well as raising their community participation.