Abstract
Background: Metabolic syndrome comprises complex health conditions. It is a risk factor of increased cardiovascular problems and it is becoming prevalent globally. To ensure proper management and treatment of metabolic syndrome, it is very important to understand its effect on various aspects of patients' lives. The aim of this systematic review is to find out the effects of MS on the quality of life (QoL) of affected individuals, involving physical, mental, and psychosocial aspects of life. Methods: This systematic review was conducted by following PRISMA guidelines and PubMed and Google Scholar were searched for articles published between 2005 and 2023. Inclusion criteria included observational and clinical studies in English, involving the studies on adults with a large sample size, focusing on the association between MS and QoL. Results: Initially 1009 articles were screened, out of the screened articles 15 met the inclusion criteria. The majority of these studies were observational. The findings indicated that MS was associated with lower overall health-related QoL scores, impaired physical health, and poor mental health. High blood pressure and abdominal obesity, core components of MS, were linked to reduced QoL. Moreover, gender-specific patterns indicated a more significant impact on females. Age was found to affect the relationship between MS and QoL, with some age groups showing different effects. Psychosocial factors, including stress and a sedentary lifestyle, were found to influence QoL in MS patients. Conclusion: This systematic review highlights the deleterious impact of MS on individuals' QoL, including physical, mental, and social dimensions. It emphasizes the need for effective management to deal with the diverse effects of MS on affected individuals and highlights the importance of psychological well-being in the management of MS. Further longitudinal studies are required to establish causal relationships and better understand the precise impact of various factors on QoL in MS patients.